Central line-associated bloodstream infection is one of most serious and common complications of central venous catheters. It is defined as a laboratory-confirmed bloodstream infection in a patient with a central line at the time of, or within 24-h prior to, the onset of symptoms, in cases where the cultured organism is not related to an infection from another site. However, prevention of that serious complication by adhering to central line care bundle is of utmost importance.
Approximately 40%–80% of CLABSIs are caused by gram-positive organisms. Coagulase-negative Staphylococci, Staphylococcus aureus, and Enterococcus are the most common organisms. Methicillin-resistant staphylococcus is frequently seen. 20%–30% of infections CLABSIs are caused by gram-negativ
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